As a former Lyme patient myself, I understand only too well the frustration of having Lyme symptoms flare, causing pain, brain fog, coordination problems and fatigue. I have tried many therapies on myself and with patients, all of which have had some success to varying degrees. Almost 2 years ago, my friend and colleague Dr. Ty Vincent introduced us to low dose immunotherapy (AKA “LDI”). He had been doing low dose allergen therapy (known as “LDA”), which is a homeopathic way to desensitize someone against food, environmental or chemical sensitivities. It is highly successful and he adopted the principles of how LDA works and applied it to other microbes that can trigger autoimmune illness once one has been exposed to a particular organism. It is well known that streptococcus (strep) can cause rheumatic heart disease or rheumatic fever, even if the strep has been treated. The bacterial cell wall has similar molecules found on our cells, so our immune system gets confused and starts reacting to our own tissues. The same thing can occur with Lyme, strep, candida and many other microbes including viruses. LDI is essentially a homeopathic preparation of inactivated organism (called a nosode for the homeopathically inclined) mixed with an enzyme called beta glucuronidase. Dr. Len McEwen, an ENT physician in the UK, found by accident that beta glucuronidase seems to help “turn off” the immune reaction to whatever is mixed with the enzyme. So if we mix a strep nosode with the enzyme, it can help shut off the overreaction to the strep. It does not seem to interfere with the normal immune mechanism our body has to appropriately fight off infection, but it does seem to shut down the overreaction to the offending microbe. These homeopathic preparations are administered sublingually generally every 7-8 weeks. In my personal and clinical experience, LDI has been one of the most clinically effective, cost-effective ways to manage Lyme symptoms. Having treated hundreds of Lyme patients, many of whom have been on antibiotics for many years, most of these folks respond favorably to LDI treatments. Unfortunately, antibiotics do not address the underlying immune problem that Lyme and other microbes cause. I find many Lyme patients, despite the length of their illness respond well to this therapy. It can take some time to find the right potency, but most patients respond well when we hit the right mark. In some cases, we have seen clinical improvement within 24-48 hours after treatment. I have read a lot of misinformation on the internet about LDI and what people should and should not do. Like any therapy, you should only do this with a doctor who is well-trained in LDI and understands proper management. But in the right hands, LDI can be a powerful tool in the recovery of Lyme disease and other chronic infections.